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ANTIGENS, HLA C
Descriptors Found:
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DeCS
Descriptor
English
:
HLA-C Antigens
Descriptor
Spanish
:
Antígenos HLA-C
Descriptor
Portuguese
:
Antígenos HLA-C
Synonyms
English
:
HLA-C
Antigens, HLA C
HLA C Antigens
Antigens, HLA-C
Tree Number:
D12.776.395.550.489.600
D12.776.543.550.439.600
D23.050.301.500.100.600
D23.050.301.500.450.390
D23.050.705.552.100.600
D23.050.705.552.450.390
Definition
English
:
Class I human
histocompatibility
(HLA)
antigens
encoded by a small cluster of structural genes at the C locus on
chromosome 6
. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk
association
with certain
disease
manifestations (e.g.,
spondylarthritis
,
psoriasis
,
multiple myeloma
).
Indexing Annotation
English
:
assoc with donor/recipient crossmatching; DF: HLA C
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23671
Unique Identifier:
D015236
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS